During my short, but very intensive stay in SF I visited many wonderful places. If you wonder what to focus on, check out my recommendations.
It all depends what type of traveler you are - maybe a foodie freak, museum lover, chiller or free spirit? No matter what is your goal, I strongly advise to take a longer walk and explore the variety that SF offers.
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There were some things and places which I didn't manage to see. Nevertheless, if you have more time it's highly recommended to go there.